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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASXL1
All Species:
16.36
Human Site:
S501
Identified Species:
40
UniProt:
Q8IXJ9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXJ9
NP_056153.2
1541
165432
S501
P
D
N
L
A
R
A
S
A
S
P
D
R
I
P
Chimpanzee
Pan troglodytes
XP_001156134
1531
163916
S491
P
D
N
L
A
R
A
S
A
S
P
D
R
I
P
Rhesus Macaque
Macaca mulatta
XP_001108038
1589
170584
S549
P
D
N
L
A
R
A
S
A
S
P
D
R
I
P
Dog
Lupus familis
XP_853069
2156
231578
K844
L
E
T
S
H
S
S
K
L
S
E
P
S
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P59598
1514
162656
S498
R
D
N
L
A
C
A
S
A
S
P
D
R
I
P
Rat
Rattus norvegicus
XP_002729264
1286
136594
T297
E
V
D
R
Q
V
G
T
D
G
L
L
R
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515168
1882
199357
S596
S
S
H
S
S
K
P
S
E
A
A
K
S
P
D
Chicken
Gallus gallus
Q5ZM88
1412
148651
K423
Q
P
K
C
M
Q
V
K
E
E
I
T
S
P
S
Frog
Xenopus laevis
NP_001086579
738
82633
Zebra Danio
Brachydanio rerio
XP_001341242
1619
172271
S545
T
A
G
T
G
A
S
S
R
E
S
S
P
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
91.1
21.7
N.A.
74
59
N.A.
28.1
26.7
29.2
27.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
93.5
36
N.A.
81.1
66.3
N.A.
41.7
41.9
36.5
41.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
86.6
6.6
N.A.
6.6
0
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
86.6
26.6
N.A.
33.3
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
40
10
40
0
40
10
10
0
0
10
10
% A
% Cys:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
40
10
0
0
0
0
0
10
0
0
40
0
0
10
% D
% Glu:
10
10
0
0
0
0
0
0
20
20
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
0
10
0
0
10
0
0
0
0
0
% G
% His:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
40
0
% I
% Lys:
0
0
10
0
0
10
0
20
0
0
0
10
0
10
0
% K
% Leu:
10
0
0
40
0
0
0
0
10
0
10
10
0
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
30
10
0
0
0
0
10
0
0
0
40
10
10
20
40
% P
% Gln:
10
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
10
0
30
0
0
10
0
0
0
50
0
0
% R
% Ser:
10
10
0
20
10
10
20
60
0
50
10
10
30
0
30
% S
% Thr:
10
0
10
10
0
0
0
10
0
0
0
10
0
0
0
% T
% Val:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _